Throughout 2020, Metformin for type 2 diabetes has experienced multiple voluntary recalls from manufacturers. The latest involves two lots of extended-release formulas from Nostrum Laboratories. Testing indicates these products contain levels of nitrosamine N-Nitrosodimethylamine (NDMA) above the FDA’s Acceptable Daily Intake (ADI) limit of 96 ng/day.
Primarily used to help control Gastroesophageal Reflux Disease (GERD), proton pump inhibitors (PPIs) are some of the most commonly used medications among American patients. They’re available by prescription and over-the-counter but are intended for short-term use. For long-term relief from GERD, patients ideally start with a PPI before transitioning to an H2 blocker.
The FDA recently announced a new label requirement for prescription opioids and medications that treat opioid use disorder (OUD).
Earlier this year, the FDA approved Invokana to reduce late-stage kidney disease and improve cardiovascular health in patients living with Type 2 diabetes and diabetic kidney disease. However, lawsuits dating back to 2015 indicate adverse cardiovascular events like heart attacks may be a side effect for certain patients.
A study from the National Safety Council indicates that more Americans die from opioids than car accidents. However, recent research indicates opioid usage may influence car fatality rates, particularly as drunk driving accidents have been on a gradual decline over the past 20 years.